As Portugal captain, I know how we've worked and we must be proud of the team. Following a corner, Ronaldo rose up, but it was the unmarked Pepe, 35, who sent home the header from behind, as the oldest Portugal player to score at a World Cup and for the first time here in Russian Federation to strike a ball into the net of Uruguay.
Suarez with 53 goals and Cavani 44 - 12 of them from assists by his striking partner - are their two all-time leading scorers and again showed their understanding with an astonishing opening goal in the seventh minute. All of Uruguay is hoping he has the chance to add more.
Uruguay and France will meet in the quarterfinals on Friday.
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England have made it through to the quarter-finals after surviving a dramatic penalty shootout against Colombia. Marcus Berg was guilty of missing some glorious chances for Sweden , who looked toothless in attack.
Luis Suarez and Edinson Cavani are lethal strikers for FCBarcelona and Paris Saint-Germain, respectively, but together they are a whole different beast, as Portugal found out in their FIFAWorld Cup 2018 Round of 16 match in Sochi on Saturday.
Portugal, who reached World Cup semi-finals back in 1966 on the back on Eusebio's nine goals, failed to get the best out of current talisman Cristiano Ronaldo. "That was an incredible play, they have never scored like that before", the 63-year-old said, ruefully.
Unsurprisingly Portugal coach Fernando Santos is hopeful that Ronaldo, who has scored 85 worldwide goals in 154 appearances, will choose to continue to represent his Country.
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De Bruyne, who is on a yellow card, will have to be wary of any caution that could prevent him from playing the quarter finals. The ball was moved downfield quickly and when Vertonghen failed to intercept the final pass, Haraguchi sprinted clear.
If Cavani doesn't recover in time, coach Oscar Tabarez could replace him with Cristhian Stuani.. "But we have a very strong team in terms of the mindset and we will always bank on the collective against any rival". France go into the match after a relatively comfortable group stage and after resting players in their last group match.
"At this stage we still believe we have room for improvement", Alves said. Obviously I'm very happy for (Cavani's) goals and that they helped us win.
We could have witnessed the changing of the guard in Argentina's 4-3 loss to France. "You need to really concentrate to make sure he is not successful against you, but that is very hard". But we will try our best and look to impose our way of playing on them, using our strengths. We have played a lot of matches [and] he hasn't had a lot of rest.
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And when he takes office in December, AMLO-as the president-elect is known-will have to please those who voted for him. Andres Manuel Lopez Obrador , a former rights activist and Mexico City mayor, has been elected president of Mexico.